GREATER MANCHESTER BIOBANKING NETWORK is an alliance and association of human research biobanks within the University of Manchester (Faculty of Medical and Human Sciences), Salford Royal Foundation Trust and Salford Care Commissioning Groups, The Christie Hospital Trust, the University Hospital of South Manchester and the Central Manchester Foundation Trust. At present all of these partners are within the Manchester Academic Health Science Network but our intention is to extend this to other appropriate academic and health care institutions across the Greater Manchester Academic Health Science Network covering a population of approximately 3 million. Membership is open to all research biobanks within the Greater Manchester Academic Health Science Network. For details of future meetings please contact us using the link above.



Salford Biorepository Facility

SALFORD BIOREPOSITORY FACILITY is located in purpose built laboratories in the Clinical Sciences Building at Salford Royal Hospital. It provides a professional sample handling and storage service to support the clinical research activities within Salford Royal Foundation Trust.


The team provides support and advice to clinicians and researchers to facilitate the collection of human research samples for clinical and academic studies, and helps ensure continued compliance with the regulatory requirements. The facility holds 9001:2008 quality management certification and operates within Medicines and Healthcare Products Regulatory Agency (MHRA) and Human Tissue Authority (HTA) guidelines.

Salford Biorepository Facility  

The facility is located within a secure laboratory area, and all users have to undergo specific training and sign up to the internal SOP's. The facility runs nine large ultra-low temperature freezers which hold human samples at -75C, to ensure that they are optimally preserved for future biomedical research. All freezers are maintained and calibrated annually and each one has its temperature automatically logged and recorded every 30 minutes to a central database that can be accessed remotely. To safeguard the samples, the freezers are equipped with emergency CO2 backup and located across three separate laboratories. Every freezer is covered by two independent temperature alarm systems.

Salford Biorepository Facility  

The vast majority of samples that are processed and stored are blood or blood derived products (e.g. serum, plasma, DNA). The facility currently stores over 65,000 samples, which have been generously provided by over 4000 donors. Its supports over 50 clinical research projects and has provided training to over 75 research staff.


For further information please contact:


Biorepository Manager:

Dr Rob Oliver, 0161 206 4405, or email Rob Oliver.


Biorepository Technician:

Julie Hudson, 0161 206 5415,or email Julie Hudson.


Biobank facilitiesMANCHESTER BRC BIOBANK is a not-for-profit service established to increase the availability and use of human biomaterials for research within academic institutions, NHS Trusts and private industry. Located on clinical academic campus within the new Centre for Advanced Discovery and Experimental Therapeutics (CADET), we supply samples of human tissue, blood, body fluids and processed derivatives for use in ethical biomedical research.


There is an open access policy for researchers who are expected to use the tissue responsibly. We are licensed by the Human Tissue Authority, have approval from the National Research Ethics Service to operate as a Research Tissue bank and are a member of the Confederation of Cancer Biobanks.


The Biobank is fully equipped for biomaterial, collection, processing and storage:

  • Frozen Storage at -80C with 24hr temperature monitoring and alarm system
  • Automated nucleic acid extraction
  • Tissue processing and histology
  • All processes managed by dedicated Laboratory Information Management System (LIMS)

We currently hold biomaterials from the following disease areas:


Gynaecological disease (including benign, malignant and control samples).

Bowel disease (including cancer, ulcerative colitis and Crohn's disease).

Head and neck, kidney, liver and prostate cancer.


For further information please contact:


Biobank Manager:

Dr Jay Brown, 0161 701 1890, or email Jay Brown.

Central Manchester Foundation Trust Central Manchester Foundation Trust


University Hospital of South Manchester logoTHE MANCHESTER RESPIRATORY AND ALLERGY BIOBANK (ManRab) is based at the University Hospital of South Manchester NHS Foundation Trust and exists in order to facilitate the performance of high quality translational research into respiratory and allergic disease.


The facility is located in a secure laboratory area and all users have to undergo specific training and read internal SOPs. All freezers are maintained and calibrated annually and each one has its temperature automatically logged. Freezers are equipped with emergency temperature alarm systems and there are contingency freezers available in the event of failure. Samples are logged onto a sample database for tracking and compliance with Human Tissue Authority (HTA) guidelines.


Blood derived products (e.g. serum, plasma, DNA, PBMCs), sputum, urine, bronchoalveolar lavage (BAL) and biopsies are available for research purposes covering disease areas of allergy, asthma, fungal lung disease, chronic cough, cystic fibrosis and interstitial lung disease. The biobank has the permission to collect for Chronic Obstructive Pulmonary Disease (COPD) and healthy volunteers, however no samples are available at present.


The biobank is involved in projects in several areas including:

  • Improved diagnosis of peanut and tree allergy
  • Causes of Chronic Cough
  • Mucin Cystic Fibrosis
  • Genetics of lung disease
  • Serology in aspergillus lung disease

The majority of applications to access tissue and data come from contributory members. ManRAB also accepts applications from non-contributory members, such as researchers from other hospitals, Universities and commercial organisations, however an access charge will be applied.


For further information please contact:


Biobank Manager:

Helen Francis, 0161 291 2847, or email Helen Francis.


THE MANCHESTER CANCER RESEARCH CENTRE BIOBANK is a multi-centre cancer biobank based at the CRUK Manchester Institute in Withington.The biobank routinely collects FFPE and frozen tumour and normal tissue with matched blood and urine from patients undergoing surgery at four NHS Trusts in the Greater Manchester area. As well as the solid tumour arm of the biobank, blood and bone marrow are also collected from patients with blood disorders such as leukaemia.


The MCRC Biobank collects samples from four collaborating NHS Trusts across the region. These are:


The Christie NHS Foundation Trust (CFT)

Salford Royal NHS Foundation Trust (SRFT)

University Hospital of South Manchester NHS Foundation Trust (UHSM)

Pennine Acute Hospitals NHS Foundation Trust (PAT)


The table below details which sample types the Biobank collects from each collaborating Trust:


In addition to the routine banking of these specimen types, the MCRC Biobank can also facilitate prospective collection of fresh tissue for culture and in-vivo work and mine the pathology archives to construct large cohort tissue microarrays linked to clinical data.


The MCRC Biobank is licensed by the Human Tissue Authority and holds Research Tissue Bank Ethical approval which can confer ethics approval to researchers using samples from the biobank. The MCRC Biobank maintains a robust approach to sample quality and biobank technicians are embedded within each hospital to ensure systems for collecting samples are standardised.


For further information please contact:


Biobank Business Manager:

Jane Rogan, 0161 446 3659, or email Jane Rogan.


Centre for Integrated Genomic Medical Research logo

THE UNIVERSITY OF MANCHESTER'S BIOBANKING team at the Centre for Integrated Genomic Medical Research (CIGMR) provide world class research infrastructure from within high-specification, automated, ISO9001:2008 accredited facilities making the University of Manchester a leader in this field.


The Centre has developed with input from multiple funders and industry partners. The centre's expertise in managing large numbers of biological samples and associated data from various disease areas has enabled collaborations with investigators across the UK and internationally by underpinning world class translational and epidemiological research. CIGMR Biobank manages the sample accrual, processing, storage and distribution for analysis of annotated samples such as DNA, plasma, serum, urine, saliva RNA and cells.


CIGMR Biobank are a 13 strong team of academics, project managers, IT specialists and sample processing technicians based in the Stopford Building at the University of Manchester. CIGMR Biobank has been active for over ten years and during this time we have successfully facilitated a large number of biobanking projects such as:


The projects we have enabled have produced a wide range of scientific publications which can be viewed on the Publications pages within the CIGMR Biobank website. Our labs use state of the art robotics in order to enable automated sample processing and storage and we run a fully customised sample tracking database (LIMS) and employ dual site storage facilities to guard against catastrophic loss of sample.


CIGMR Biobank was the first academic biobank to gain ISO9001:2008 certification in 2005;  quality management is at the core of our operations and we are actively pursuing a policy of quality improvement within the department.


CIGMR Biobank is a member of P3G (Public Population Projects in Genomics), ISBER (International Society for Biological and Environmental Repositories) and CCB (Confederation of Cancer Biobanks).


For further information please contact:


Biobank Operations Manager:

Kate Dixon, 0161 275 1625, or email Kate Dixon.


Manchester Brain Bank

The work of the MANCHESTER BRAIN BANK is to collect and supply human brain tissues for research, locally, nationally and internationally. The Brain Bank is principally supported by Alzheimer's Research UK and Alzheimer's Society, through Brains for Dementia Research initiative, but also receives support from MRC via the national brain banking network.


Brains from prospectively assessed individuals with neurodegenerative diseases, and healthy controls, are collected via a brain donation programme, and tissues are made available through application to the Brain Bank. Tissues are available as preserved or frozen samples, as tissue blocks or glass mounted sections, and can be employed in a range of histological, immunohistochemical, biochemical and genetic analyses.


Manchester Brain BankMore than 750 specimens are currently housed in the Brain Bank, most of which have both preserved and frozen tissues available.The Brain Bank has made major contributions to the identification of the major genetic mutations associated with Frontotemporal Lobar Degeneration and to the clinical diagnostic criteria and molecular pathological classification of the main neurodegenerative diseases.


For further information please contact:


Manchester Brain Bank Manager:

Andrew Robinson, 0161 206 4408, or email Andrew Robinson.


The following is an up to date summary of the most recent biobanking related publications as provided by Feedwind. This RSS feed is updated on a weekly basis.




Membership is open to all research biobanks within the Greater Manchester Academic Health Science Network.


In order to join and for details of future meetings please contact:


Kate Dixon, Operations Manager, CIGMR Biobank, tel. 0161 275 51625 or email Kate Dixon.

Margaret Stark, IT Support, CIGMR Biobank, tel. 0161 275 1623 or email Margaret Stark.

      Greater Manchester Biobanking Network map


In May 2014 CIGMR BIOBANK Quality Manager, Emma Davis and Operations Manager, Kate Dixon attended a 5 day long educational visit to Karolinska Biobank in Stockholm, Sweden. The visit enabled staff from both Biobanks to swap knowledge and ideas, fostered collaboration and strengthened links between the Manchester and KI biobanks. The visit included a trip to ThermoFisher, Upsalla to learn about a new prostate cancer biomarker screening project which is being piloted by the Swedish Stockholm 3 trial investigating new ways of predicting risk of prostate cancer in men.


The CIGMR BIOBANK continues to support Professor Catherine West’s FP7 funded Study of REQUITE: Validating predictive models and biomarkers of radiotherapy toxicity to reduce side-effects and improve quality-of-life in cancer survivors. The study is collecting samples from 10 geographical sites across Europe and the United States which will be forwarded to CIGMR BIOBANK for processing and distribution to analysis centres. Genevieve Pridham, a project manager from the CIGMR BIOBANK, has visited 7 of the sites in the past 2 months, providing advice and training, as well as conducting site initiation visits to help collaborating sites to prepare for their sample collection activities.


The CIGMR BIOBANK continues to be busy supporting researchers from within the U-Biopred project. The project aims to accelerate drug development for Asthma sufferers and the CIGMR BIOBANK has played a key role in the project over the past 4 years by organising the collection of approximately 40, 000 aliquots of biological samples from donors across Europe. In the past 6 months alone the CIGMR BIOBANK has distributed 3146 samples for transcriptomics, biomarker analysis, metabolomics and genetic analysis at collaborating analysis sites across Europe and the US.


SALFORD BIOREPOSITORY FACILITY has recently gained ISO9001:2008 certification. This internationally recognised quality management standard is an endorsement of the high quality systems which the facility operates, with a recognised commitment to process improvement, training, document control and record-keeping. This builds on the existing regulatory compliance that is already in place relating to the Human Tissue Authority (HTA) and the Medicines and Healthcare products Regulatory Authority (MHRA).


MANCHESTER BIOMEDICAL RESEARCH CENTRE have recently provided tissue handling and histology support for a trial of anti-HIV drug lopinavir in women with cervical cancer. The trial was led by Drs Ian and Lynne Hampson, from the University's Institute of Cancer Sciences in collaboration with Dr Innocent Orora Maranga at Kenyatta National Hospital in Nairobi.


ADDITIONALLY, after a successful pilot study on the treatment of endometrial cancer with metformin, lead investigator Dr Emma Crosbie, Consultant in Gynaecological Oncology, is planning to start a Randomised Placebo Controlled Trial in 2014 with further support from the biobank.


MANRAB has recently begun collecting samples in Interstitial Lung Disease (ILD) and now has ethical approval to recruit patients with bronchiectasis. Recruitment is steadily increasing and ia fast approaching the milestone of 2000 patients recruited to ManRAB. In order to meet the resulting increased storage requirements, ManRAB has recently expanded their capacity in terms of the number of freezers available.


MANCHESTER CANCER RESEARCH CENTRE BIOBANK has recently been selected as the collection centre for the Genomics England 100K Genome Project. This comes as a result of the MCRC Biobank’s success at delivering Phase 1 of the CRUK Stratified Medicine Programme. The project consists of a 7 month collection of specimens across 5 disease groups, whereby DNA will be extracted from tumour and blood samples from over 300 patients for whole genome sequencing.